Inteins in mycobacterial GyrA are a taxonomic character.

نویسندگان

  • P Sander
  • F Alcaide
  • I Richter
  • K Frischkorn
  • E Tortoli
  • B Springer
  • A Telenti
  • E C Böttger
چکیده

The A subunit of DNA gyrase in mycobacteria is frequently subjected to splicing events as its gene, gyrA, harbours an insertion encoding an intein. Investigation of a number of different isolates of Mycobacterium kansasii, Mycobacterium malmoense, Mycobacterium marinum, Mycobacterium ulcerans and Mycobacterium xenopi demonstrated that the presence of GyrA inteins is not random but a taxonomic character specific for a given taxon at a species or subspecies level.

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Development of a positive genetic selection system for inhibition of protein splicing using mycobacterial inteins in Escherichia coli DNA gyrase subunit A.

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عنوان ژورنال:
  • Microbiology

دوره 144 ( Pt 2)  شماره 

صفحات  -

تاریخ انتشار 1998